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PRECeDI - Personalized pREvention of Chronic DIseases 

EUPHA's role in PRECeDI 

PRECeDI promotes international and inter-sector collaboration through research and innovation staff exchanges, and sharing of knowledge and ideas from research to market (and vice-versa) for the advancement of science and the development of innovation. PRECeDI started in January 2015 and was completed in November 2018. EUPHA was one of the partners, hosting researchers from other organisations. In hosting the researchers, EUPHA closely worked together with the Department of Clinical Genetics, VU University Medical Centre, Amsterdam.

The aim of the PRECeDI consortium was to promote knowledge transfer between academic and non-academic entities that can lead to a proper integration of –omics information into public health interventions. The main goal of this platform was to cover an existing gap in the evidence-base use of the –omics approach in the prevention of chronic diseases, by sharing knowledge, building synergies and expertise and encouraging an exchange of best practice among top-level institutions. In the long run, the results of the consortium activities will enhance the scientific basis for an appropriate implementation of the –omics applications into true benefits for population health.

PRECeDI facilitated collaboration in the form of joint research and innovation activities across five domains of personalized prevention of chronic diseases:

  1. Identification of biomarkers for the prevention of chronic diseases
  2. Economic evaluation of predictive genomic applications
  3. Ethico-legal and policy issues surrounding personalized medicine
  4. Sociotechnical analysis of the pros-and cons of informing healthy individuals on their genome
  5. Identification of organizational models for the provision of predictive genetic testing

The PRECeDI project received funding from the European Union’s Horizon 2020 research and innovation programme Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE) under the grant agreement No. 645740.

PRECeDI was coordinated by the Catholic University of the Sacred Heart of Rome (Italy). The consortium consisted of 11 partners from different European Countries, USA, Canada, of which 7 are academic institutions and 4 non academic organisations, including EUPHA.

Secondments with EUPHA

EUPHA hosted Peter Piko from the University of Debrecen, Hungary, who worked on the pros and cons of informing healthy individuals on their genome (primary prevention healthy family members).  

Elvira d'Andrea, La Sapienza University, Rome, Italy, conducted a systematic review of literature on genetic testing and looked into the cost-effectiveness of screening for Familial Hypercholesterolemia and Lynch Syndrome.  

Alessia Tognetto, Catholic University of the Sacred Heart (UCSC), Rome, Italy, conducted a systematic review on the existing screening pathways for Lynch Syndrome identification.

Researchers from La Sapienza University of Rome, Annalisa Rosso, Elvira d'Andrea and Valentina Baccolini, worked on a survey aimed at assessing European public health professionals’ knowledge and attitudes regarding the practical application of Public Health Genomics (PHG).

Vladimir Vukovic (UCSC) studied recurrent disease and second primary malignancies in head and neck cancer.

More information on the project website.