On 22 June, the European Commission launched an important initiative to support EU Member States to reduce the burden of EU Non-Communicable Diseases (NCDs) by addressing the leading causes of avoidable premature death in Europe and improving citizens' health and well-being. To do so, the Commission has published a guiding document to the “Healthier Together: EU Non-Communicable Diseases (NCDs) Initiative”. This Initiative identifies effective actions and the available legal and financial supporting tools across five main areas: cardiovascular diseases, diabetes, chronic respiratory diseases, mental health and neurological disorders, as well as their main contributing factors. The Initiative will have a budget of €156 million under the 2022 work programme of the EU4Health programme.